-- Robert Preidt
TUESDAY, April 12 (HealthDay News) -- Cases of AIDS-related
cancers have decreased among people with HIV in the United States,
but other types of cancer are on the rise in this group, a new
study has found.
Three cancers -- Kaposi's sarcoma, non-Hodgkin's lymphoma and
invasive cervical cancer -- are among the diseases included in the
criteria that the U.S. Centers for Disease Control and Prevention
uses to determine whether a person with HIV has developed AIDS.
The study, by researchers from the U.S. National Cancer
Institute and the U.S. Centers for Disease Control and Prevention,
found that these AIDS-defining cancers decreased threefold, from
34,000 cases between 1991 and 1995 to about 10,000 cases between
2001 and 2005.
They attributed the decrease to the introduction in 1996 of
highly active antiretroviral therapy, which improves immune
function, reduces risk of progression to AIDS and greatly improves
survival among people infected with HIV.
But the study also found that the total number of all other
types of cancers in people with HIV tripled, from about 3,000 cases
between 1991 and 1995 to about 10,000 cases between 2001 and
The findings were published online April 11 in the
Journal of the National Cancer Institute.
"Our study observed striking increases for a number of malignancies related to cancer risk factors that are known to be prevalent in this population, such as smoking and infection with cancer-causing viruses," study author Meredith S. Shiels, from the division of cancer epidemiology and genetics at the National Cancer Institute, said in a journal news release. "We also observed increases for nearly all other cancers, which is what one might expect for an aging population."
Senior investigator Dr. Eric A. Engels, a colleague of Shiels,
said in the release that "the changing number and types of cancer
for people with HIV/AIDS highlights the need for research focusing
on the specific cancer prevention needs of this population,
including smoking cessation, treatment of hepatitis B and C viral
infections and prevention and screening for HPV-related
The U.S. National Institute of Allergy and Infectious Diseases
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