-- Robert Preidt
THURSDAY, April 28 (HealthDay News) -- Women are much more
likely than men to sustain kidney damage after undergoing a common
heart imaging test called coronary angiography, a new study has
During the procedure, an iodine contrast dye is used to enhance
images of the heart's blood vessels and chambers. But the dye may
cause the kidney's blood vessels to narrow, damaging the organ,
explained Dr. Javier Neyra, an internal medicine resident at Henry
Ford Hospital in Detroit and the study's principal
The side effect, known as radiocontrast-induced nephropathy, can
cause kidney dysfunction within 24 to 72 hours after the dye has
been injected. In the United States, it is the third-leading cause
of hospital-acquired kidney damage, after surgery and high blood
pressure, according to the study.
"Because men and women patients receive the same amount of dye during a coronary angiogram, it's possible the amount is just too much for a woman's body to handle given her smaller size," Neyra said in a hospital news release. "Perhaps a woman's height and weight ought to be factored into the dosage."
For their study, the researchers followed 1,211 people who had a
coronary angiogram between January 2008 and December 2009. They
found that women were 60 percent more likely than men to develop
radiocontrast-induced nephropathy -- 20 percent versus 13.6
The findings were to be presented Wednesday at a National Kidney
Foundation meeting in Las Vegas. Experts note that research
presented at meetings should be considered preliminary because it
is not subjected to the rigorous scrutiny given to research
published in medical journals.
The U.S. National Heart, Lung and Blood Institute has more about
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