THURSDAY, Sept. 20 (HealthDay News) -- The number of people who
survive surgery when general anesthesia is used has improved
dramatically over the past 50 years, Canadian researchers
The improvement was noted worldwide, with most of the increases
in survival seen in developed countries, the researchers added.
Overall, there was a 90 percent drop in such deaths since before
"Anesthesia safety continues to improve, and we should continue to find ways to make it even safer," said lead researcher Dr. Daniel Bainbridge, from the department of anesthesia and perioperative medicine at the University of Western Ontario.
"We have done a good job to reduce risk of anesthesia," he said. "However, it is similar to the airline industry in that passengers tend to be very concerned about dying while flying, likewise they also are concerned about dying [while] under anesthesia, so the question is whether we can reduce the rates even further."
The rate of improved safety, however, was lower in developing
countries, Bainbridge said.
"More attention needs to be paid to taking care of those in less well-off countries, and these efforts are already under way but should be supported to a greater degree," he added.
The report was published in the Sept. 22 issue of
For the study, Bainbridge's team culled data from 87 studies
spanning more than 60 years on anesthesia deaths. Specifically,
they focused on how people fared in the two days after surgery.
The studies they analyzed contained data on more than 21.4
million cases in countries around the world, the researchers
This type of study is called a meta-analysis, where researchers
try to find common connections between a variety of different
studies. The main problem with this kind of study is bias in
selecting studies for analysis and forcing different data together
that were not intended to be combined.
In their analysis, Bainbridge's group found that although more
high-risk and complicated surgeries are being done now than before,
the odds of dying after being given a general anesthetic has
dropped about 90 percent.
Before the 1970s, about 357 of every 1 million patients died,
but from the 1990s to 2000s that number dropped to 34 patients per
Over the same period, the risk of dying in the first 48 hours
after surgery dropped about 88 percent, from just over 10,000 per
million before the 1970s to nearly 1,200 per million in the
1990s-2000s, the investigators found.
Although these advances were seen all over the world, two to
three times more patients survive surgery in developed countries
than do in developing countries, Bainbridge said.
There are several reasons for this dramatic decline, one expert
"One obvious factor is advances in medicine in a culture of safety," said Dr. Michael Avidan, a professor of anesthesiology and surgery and division chief of cardiothoracic anesthesia and cardiothoracic intensive care at Washington University School of Medicine in St. Louis. He co-authored an accompanying journal editorial.
"We have safer drugs, we have better monitoring, we have better training, we have better safety drills," Avidan said. "Many of these advances are fairly low-tech and have immediate applicability throughout the world."
These include surgery checklists, and more practice and
training, as well as better communication among members of the
surgical team, he noted.
Most deaths during surgery or shortly after are not the result
of just one failing, he added.
Avidan also noted that while deaths after surgery have declined,
sometimes these are only "deaths deferred," as the patient is
sometimes so sick or frail that he or she is likely to die within a
month or two after surgery.
Another paper in the same journal issue showed the standard
practice of changing intravenous catheters placed after surgery
every three days may be unnecessary.
The researchers say changing them only when needed would prevent
millions of painful procedures and dramatically cut material and
"Of the 200 million catheters estimated to be inserted each year in the U.S.A. alone, if even 15 percent are needed for more than three days, then a change to clinically required replacement would prevent up to 6 million unnecessary intravenous catheter insertions, and would save about 2 million hours of staff time, and up to US$60 million in health costs each year for that country alone," lead researcher Claire Rickard, from Griffith University in Australia, said in a journal news release.
For more on surgery safety, visit the
U.S. Agency for Healthcare Research and
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