-- Robert Preidt
TUESDAY, Nov. 19, 2013 (HealthDay News) -- People with a certain
type of epilepsy have widespread, abnormal brain connections that
could provide clues for diagnosis and treatment, new research
The study included 24 people with left temporal lobe epilepsy,
the most common form of focal (partial) epilepsy. Partial seizures
do not involve the entire brain. People with temporal lobe epilepsy
experience seizures that start in the temporal lobe. These are
located on each side of the brain, just above the ears.
Researchers used MRI to compare the brains of the epilepsy
patients and a group of 24 people without epilepsy. Epilepsy
patients had 22 percent to 45 percent fewer long-range connections
in the brain's "default-mode network" compared to people without
This set of brain regions is active when the mind is at rest and
allowed to wander or daydream.
The epilepsy patients also had 85 percent to 270 percent more
local connections within and beyond the default-mode network. This
may be an adaptation to having fewer long-range connections, noted
the study authors.
The findings are published in the Nov. 19 online edition of the
"Our long-term goal is to see if we can we predict . . . who will respond to surgery and who will not," Dr. Steven Stufflebeam, of Massachusetts General Hospital, said in a journal news release.
The U.S. Centers for Disease Control and Prevention has more
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