-- Robert Preidt
FRIDAY, Feb. 7, 2014 (HealthDay News) -- U.S. veterans of the
Vietnam War who were exposed to the herbicide Agent Orange may be
at increased risk for skin cancer, a new study warns.
Agent Orange was a chemical spray that was widely used during
the Vietnam War to clear foliage in the jungle. It contained a
known carcinogen called dioxin, and has been linked to a wide range
of cancers and other diseases.
Researchers analyzed the medical records of 100 men who joined
the Agent Orange registry at the Veterans Affairs Hospital of
Washington, D.C., between August 2009 and January 2010. The men
lived or worked in contaminated areas (56 percent), were involved
in the spraying of Agent Orange (30 percent), and traveled in
contaminated areas (14 percent).
Only men with lighter skin types were included in the study.
The rate of non-melanoma invasive skin cancer among these
veterans was 51 percent, which is about twice as high as among
same-aged men in the general population. The risk of skin cancer
was highest (73 percent) among veterans who were involved in the
spraying of Agent Orange. The risk was also higher among men with
the lightest skin types and lighter eyes.
Forty-three percent of the study participants had a skin
condition called chloracne, which is caused by exposure to dioxins,
the investigators found. In this group of men, the rate of
non-melanoma invasive skin cancer was more than 80 percent.
But for malignant melanoma, which is the most dangerous type of
skin cancer, the researchers found no increased risk. The rate of
this type of deadly cancer among the veterans exposed to Agent
Orange was similar to that among men of similar age in the general
population, the study authors noted in a journal news release.
The findings were published in the February issue of the journal
Plastic and Reconstructive Surgery.
However, two of the veterans had unusually aggressive
non-melanoma invasive skin cancer with many recurrences that
required numerous surgeries, the report revealed.
The findings add to previous evidence that people exposed to
Agent Orange are at increased risk for non-melanoma invasive skin
cancer, even decades after exposure, concluded Dr. Mark Clemens, of
the University of Texas M.D. Anderson Cancer Center, and
"Further studies are warranted to determine the relative risk within this patient population and to determine appropriate management strategies so that veterans may receive the care they earned in service," the study authors wrote.
The U.S. Department of Veterans Affairs has more about
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