Although primarily used on a short-term basis to treat attacks of gout, colchicine is increasingly being prescribed for longer periods as a gout preventive. This practice may heighten the chance of developing the nutritional deficiency discussed here.
Colchicine can impair intestinal absorption of vitamin B
12, so taking a B
12 supplement during extended colchicine therapy may be warranted.1
Webb DI, Chodos RB, Mahar CQ, et al. Mechanism of vitamin B12 malabsorption in patients receiving colchicine.
N Engl J Med
279: 845850, 1968.
Last reviewed September 2014 by EBSCO CAM Review Board
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © EBSCO Publishing. All rights reserved.