(HealthDay News) -- It's never a good idea to drink alcohol while you're taking a medication, but there are certain over-the-counter drugs that can be particularly dangerous when taken with alcohol.

The American Academy of Family Physicians says these OTC medications should never be taken with alcohol:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, aspirin or naproxen.
  • Acetaminophen (the active ingredient in Tylenol).
  • Antihistamines that tend to cause drowsiness.
  • Medications to manage cough and congestion that contain dextromethorphan.
  • Herbs, notably supplements that contain valerian root, kava kava or St. John's wort.