SATURDAY, May 18 (HealthDay News) -- A new device that gives
doctors a better view during colonoscopies may help them miss fewer
suspicious growths during those exams, a new study shows.
Colonoscopies are the recommended screening tests for colorectal
cancer, which is the second leading cancer killer of men and women
in the United States.
To perform a colonoscopy, doctors use a long, flexible tube with
a camera mounted on the end called a colonoscope to view the lining
of the large intestine.
The basic design of those devices hasn't changed in about 30
years, said study author Dr. Ian Gralnek, a senior physician at the
department of gastroenterology at Rambam Health Care Campus and
Elisha Hospital in Haifa, Israel.
And the design isn't perfect. A February 2006 study published in
American Journal of Gastroenterologyfound that traditional
colonoscopies missed 22 percent of polyps. Polyps are fleshy
growths on the walls of the colon that can turn into cancers if
they aren't removed.
Part of the problem, Gralnek explained, is that scopes only have
one forward-facing camera, which gives doctors a 170-degree view.
That makes it easy to miss polyps, which often grow behind fleshy
folds on the colon walls.
To improve detection, an Israeli company has designed a new
colonoscope, called the Full Spectrum Endoscopy, or FUSE. The FUSE
colonoscope uses three cameras mounted on the front and sides of a
flexible arm to give doctors a 330-degree view as they work.
EndoChoice of Alpharetta, Ga., the company that's acquired the
rights to the device, funded the study.
Gralnek tested the new technology by asking 183 stalwart
patients to undergo back-to-back colonoscopies.
About half of the patients were randomly assigned to have a
colonoscopy with a traditional colonoscope, followed by the same
test using the new FUSE scope. In the other half, the order of the
tests was reversed.
During the first test, doctors found and removed as many polyps
as they could see. They used the second test to count the number of
polyps that were missed on the first go-round.
The FUSE scope missed about 8 percent of adenomas -- small, flat
polyps that are especially concerning to doctors because they can
turn into full-blow cancers. The standard colonoscopes missed about
43 percent of those growths.
"You really see a lot better [with the FUSE scope]," Gralnek said. "The natural anatomy of the colon has these folds. You can miss polyps on the back sides of these folds and at some of the twists and turns within the colon itself. Because of the extra cameras we're seeing a lot more of the colon itself."
An expert who was not involved in the research says the
technology is worth further study.
"These are important data," said Dr. Frank Sinicrope, a professor of medicine and oncology at the Mayo Clinic in Rochester, Minn.
But Sinicrope said it's still not clear whether the new
technology will actually prevent more colon cancers than
traditional colonoscopies do.
"Detecting more polyps and adenomas does not necessarily indicate that a reduction in cancer risk or mortality will result, since many small adenomas may never develop into cancers," he pointed out.
It's logical that finding more adenomas would make the test more
effective, but he points out that hasn't been proven yet.
The study was to be presented Saturday at the Digestive Diseases
Week annual meeting in Orlando.
Research findings presented at medical conferences are
considered preliminary because they haven't yet had the scrutiny
that's required for publication in a peer-reviewed journal.
Until the new technology is ready for widespread use, the most
important thing to do is to go for a colonoscopy.
The American Cancer Society recommends that men and women of
average risk get colonoscopies every 10 years, starting at age
For more on colonoscopies, head to the
U.S. National Institutes of Health.
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