-- Robert Preidt
TUESDAY, Oct. 15 (HealthDay News) -- People with moderate to
severe psoriasis are at increased risk for chronic kidney disease
and need to be closely monitored for kidney problems, a large new
Researchers in Philadelphia analyzed data from nearly 144,000
people, aged 19 to 90, with psoriasis, and a comparison (control)
group of nearly 690,000 adults without the condition.
During seven years of follow-up, people with psoriasis were more
likely to develop chronic kidney disease than those in the control
group. Those with severe psoriasis had a nearly two-fold higher
risk of developing kidney disease and a more than fourfold higher
risk of developing kidney failure requiring dialysis, according to
a journal news release
Further investigation that focused on the amount of skin area
affected by psoriasis showed that people with moderate to severe
psoriasis were at greater risk of developing chronic kidney
disease. People with moderate psoriasis have 3 percent to 10
percent of skin area affected, while those with severe psoriasis
have more than 10 percent of skin area affected.
Psoriasis is a chronic condition involving scaly skin patches
that can lead to itching, cracking and bleeding. As many as 7.5
million Americans have the autoimmune condition, according to the
National Psoriasis Foundation.
Moderate and severe psoriasis affect more than 20 percent of
patients worldwide, according to the study, which appears Oct. 15
in the journal
Although the study found an association between having psoriasis
and a higher risk of kidney problems, it did not establish a
The researchers also found that the risk of chronic kidney
disease linked to psoriasis increases with age. In patients aged 40
to 50 with severe disease, psoriasis accounted for one extra case
of chronic kidney disease per 134 patients yearly. In those aged 50
to 60, it accounted for one extra case yearly per 62 patients.
Further research is needed to confirm the study findings,
determine how psoriasis can cause kidney disease and examine how
psoriasis treatment affects the risk for kidney disease, the
The American Academy of Family Physicians has more about
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