Diane Safer, PhD
Related Media: What is Metabolic Syndrome?
The metabolic syndrome is not a disease, but rather a group of risk factors for heart disease.
Elevated blood pressure, abnormal lipid levels, large waistline and a high fasting blood glucose level are all risk factors that can make up metabolic syndrome.
According to the American Heart Association, metabolic syndrome affects 35% of adults in the United States. It is important to be tested for these risk factors and have them managed because they put you at a higher risk for a number of serious conditions, including
type 2 diabetes,
heart attack, and
About metabolic syndrome. American Heart Association website. Available at:
http://www.heart.org/HEARTORG/Conditions/More/MetabolicSyndrome/About-Metabolic-Syndrome_UCM_301920_Article.jsp. Updated August 16, 2012. Accessed February 22, 2013.
Gami AS, Witt BJ, Howard DE, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies.
J Am Coll Cardiol. 2007;49:403-414.
Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor.
J Clin Endocrinol Metab. 2007;92:399-404.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome.
Metabolic syndrome. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed/what. Updated January 9, 2013. Accessed February 22, 2013.
Ridker PM, Wilson PWF, Grundy SM. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
Steinberger J, Daniels SR, Eckel RH, et al. AHA scientific statement: progress and challenges in metabolic syndrome in children and adolescents.
4/15/2011 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed/: Mottillo S, Filion KB, Genest J, Joseph L, et al. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol.
Last reviewed May 2014 by Michael Woods, MD
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