Clinical Trials

Study Title

An intermediate access protocol for selumetinib for treatment of neurofibromatosis type 1 with inoperable, progressive/symptomatic plexiform neurofibromas

Purpose

To provide access to selumetinib to people with neurofibromatosis type 1 (NF1) with plexiform neurofibromas that cannot be operated on.

Eligibility

Patients ≥ 2 years old with disease before the age of 18 years old

Diagnosis of neurofibromatosis type 1 (NF1)

Plexiform neurofibromas that cannot be surgically completely removed

Study Process

There is no maximum duration for this study as long as it is deemed that a response is being obtained.