Cordyceps

Supplement Forms/Alternate Names:

  • Dongchongxiacao
  • Cordyceps sinensis
  • Ophiocordyceps sinensis

Introduction

Cordyceps is a fungus that grows in China. It has been used to improve kidney function and help the body fight illness. Cordyceps can be taken as a pill, powder, or extract. It can also be made into a tea.

Dosages

1 to 5 grams once daily

What Research Shows

May Be Effective

  • Chronic kidney disease—may provide benefit when used with standard treatment A1
  • Kidney transplant support—may provide benefit when used with standard treatment C1, C2

Not Enough Data to Assess

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take cordyceps in small doses for a short time. Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.
Interactions
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.

References

A Chronic Kidney Disease
A1 Zhang HW, Lin ZX, et al. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease. Cochrane Database Syst Rev. 2014 Dec 18;(12):CD008353.
B Diabetic Kidney Disease
B1 Luo Y, Yang SK, et al. Use of Ophiocordyceps sinensis (syn. Cordyceps sinensis) combined with angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) versus ACEI/ARB alone in the treatment of diabetic kidney disease: a meta-analysis. Ren Fail. 2015 May;37(4):614-634.
C Kidney Transplant Support
C1 Hong T, Zhang M, et al. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients. Cochrane Database Syst Rev. 2015;(10):CD009698.
C2 Ong BY, Aziz Z. Efficacy of Cordyceps sinensis as an adjunctive treatment in kidney transplant patients: A systematic-review and meta-analysis. Complement Ther Med. 2017 Feb;30:84-92.

Revision Information

  • Reviewer: EBSCO NAT Review Board Eric Hurwitz, DC
  • Review Date: 02/2020
  • Update Date: 06/22/2020