-- Scott Roberts
FRIDAY, Oct. 7 (HealthDay News) -- The erectile dysfunction drug
Cialis (tadalafil) has received new approval from the U.S. Food and
Drug Administration to treat benign prostatic hyperplasia (BPH),
the medical term for an enlarged prostate.
Symptoms of BPH frequently include difficulty urinating, a
sudden urge to urinate, and an increase in having to urinate,
notably at night.
The drug was evaluated among men with BPH in three trials. Those
who took 5 milligrams of Cialis once daily showed significant
reduction in symptoms of BPH, the FDA said in a news release. The
third trial involved men with BPH who also had been diagnosed with
Men who take a class of drugs called nitrates, including
nitroglycerin, shouldn't take Cialis in tandem, since the
combination could lead to an unsafe drop in blood pressure, the FDA
said. The agency made a similar warning about taking Cialis along
with alpha blocker drugs, which typically are prescribed to treat
high blood pressure or anxiety.
Eight other drugs have been approved to treat symptoms of BPH:
Proscar (finasteride), Avodart (dutasteride), Jalyn (dutasteride
and tamsulosin), Hytrin (terazosin), Cardura (doxazosin), Flomax
(tamsulosin), Uroxatral (alfuzosin) and Rapaflo (silodosin).
Cialis is produced by Indianapolis-based Eli Lilly and Co.
The U.S. National Library of Medicine has more about
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