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Clinical Trials

Clinical Trials
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Clinical Trials

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  • A Phase 2, multi-center, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of topically-applied AG013 for the attenuation of oral mucositis in subjects with cancers of the head and neck receiving concomitant chemoradiation therapy.

    To determine the effectiveness as well as safety & tolerability of AG013 in altering the onset, course & severity of oral mucositis compared to placebo (a mouth rinse which looks exactly the same as AG013 but which dose not contain AG013) when administered 3 times each day.

  • 14.0012 - Evaluation Tracking Project: A Prospective Chart Review of Patients Treated with Radiation Therapy

    To collect & analyze information on people with similar cancer diagnosis. The effectiveness of procedures & treatments, the usefulness of various tests, and the incidence of short or long-term side effects will be evaluated. The ultimate goal is to improve effectiveness of treatments & procedures & limit side effects & late complications for patients.

  • 16.0001 - Pragmatic Phase III Randomized Trial of Proton versus Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

    To compare 2 types of standard care radiation treatment: photon and proton, to find out which type is best for treating non-metastatic breast cancer.

  • Pivotal, open-label, randomized study of radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 brain metastases from non-small cell lung cancer (NSCLC)

    To obtain information on the safety & effectiveness of the NovoTTF-100M (study device) in patients with brain metastases (tumors) from non-small cell lung cancer.

  • 17.0008 - A Pivotal, Double-blind, Randomized, Placebo-controlled, Multinational Study of SGX942 (Dusquetide) for the Treatment of Oral Mucositis in Patients being Treated with Concomitant Chemoradiation for the Treatment of Squamous Cell Carcinoma of the Head and Neck

    To test the safety & efficacy of SGX942 in any resulting oral mucositis in patients with squamous cell carcinoma of the head and neck who will also receive treatment with chemotherapy and radiation therapy

  • A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer (COMPPARE)

    To determine if prostate cancer patients treated with proton therapy, as compared to IMRT, experience:

    Improved quality of life

    Reduced toxicity

    Non-inferior or even superior cancer control

    To determine if Hypofractionated proton therapy is non-inferior to standard fractionated proton therapy in patient-reported outcomes & physician-reported toxicity.

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