This disease lowers the body's ability to fight infections. It reduces the body's white blood cells. And without the antibodies that white blood cells make, it's hard for the body to fight off attacks by bacteria and viruses.


Doctors don't always know what causes hypogammaglobulinemia. It can be present at birth. Most children who are born with it will grow out of it while they are still young. This disease can also develop later in life. It can be a lifelong problem for some people.


Symptoms include frequent infections and respiratory problems. The disease can lead to infections in the sinuses and the ears. And it can lead to gastrointestinal problems.


Treatment options depend on the patient's needs. Options include medications and therapies to boost the immune system. A stem cell transplant may be helpful for some patients.