Endometrial Biopsy


This diagnostic procedure is used to collect a small tissue sample from the endometrium, the layer of tissue that lines the uterus, so that the cells can be examined under a microscope. Endometrial biopsy is performed on an outpatient basis, and takes about 5 to 15 minutes to complete.


In preparation for the procedure, the patient is positioned and a speculum is inserted into the vagina to expose the cervix. A local anesthetic may be administered, but in many cases, no anesthesia is needed. The cervix is cleansed with an antiseptic wash.

Accessing the Uterus

The physician inserts a thin, hollow suction tube through the cervix and into the uterus. Specialized forceps may be used to grasp and support the cervix, if needed. In some cases, dilation rods may be inserted to expand the opening of the cervix so that the suction tube can be inserted.

Collecting the Sample

The physician advances the suction tube to the uterine wall, and uses it to carefully collect a small sample of endometrial tissue.

End of Procedure and Aftercare

Once the sample has been collected, the instruments are removed and the patient is allowed to go home. The sample is sent to a lab for analysis. The physician will provide specific aftercare instructions and follow up with lab results.