- A Master Protocol Assessing the Safety, Tolerability, and Efficacy of Anti-Spike (S)
SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Patients with
COVID-19 (Regeneron 2067)
This research study is looking at treatment with Regeneron Monoclonal Antibody Treatment for Covid-19 positive expectant mothers and children. The study drug targets the virus that causes COVID-19 and may make it harder for the virus to infect you further. The goals of the study include seeing whether the drug reduces the need for medical visits. ALL QUALIFIED PATIENTS RECEIVE REGENERON MONOCLONAL ANTIBODY TREATMENT.
- A multi-center, adaptive, prospective, randomized trial evaluating the efficacy and safety of antithrombotic strategies in patients with Covid-19 following discharge. (Activ)
To determine if a blood thinner medication can prevent blood clots from developing in patients recently hospitalized with Covid-19.
- A Phase 2/3 Postexposure Prophylaxis Study of PF-07321332/Ritonavir in Household Contacts of a Patient with COVID-19. (Pfizer 1006)
To compare the efficacy of 5-day and 10-day regimens of PF-07321332/ritonavir versus placebo in preventing symptomatic RT-PCR+ SARS-CoV-2 infection in adult participants who are household contacts of a patient recently diagnosed with symptomatic Covid 19.
- A Phase 3, Randomized, Observer-Blinded, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine (SARS-CoV-2 rS) with Matrix-M1™ Adjuvant in Adult Participants = 18 Years with a Pediatric Expansion in Adolescents (12 to < 18 Years) (Novavax)
To evaluate the efficacy of a 2-dose regimen of SARS-CoV-2 rS adjuvanted with Matrix-M1 compared to placebo against polymerase chain reaction (PCR)-confirmed symptomatic coronavirus disease 2019 (COVID-19) illness diagnosed ≥ 7 days after completion of the second injection in the initial set of vaccinations of adult participants ≥ 18 years of age.
- 20.0004 - The COVID-19 and Cancer Consortium (CCC19) Registry
To collect granular information on cancer patients infected with COVID-19.